Joint Population Pharmacokinetic Analysis of Zidovudine, Lamivudine, and Their Active Intracellular Metabolites in HIV Patients

The population pharmacokinetic parameters of zidovudine (AZT), lamivudine (3TC), and their active intracellular metabolites in 75 naïve HIV-infected patients receiving an oral combination of AZT and 3TC twice daily as part of their multitherapy treatment in the COPHAR2-ANRS 111 trial are described....

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Autors principals: Bazzoli, C., Bénech, H., Rey, E., Retout, S., Salmon, D., Duval, X., Tréluyer, J. M., Mentré, F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122424/
https://ncbi.nlm.nih.gov/pubmed/21576446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01487-10
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