O-Linked-N-Acetylglucosamine Cycling and Insulin Signaling Are Required for the Glucose Stress Response in Caenorhabditis elegans

In a variety of organisms, including worms, flies, and mammals, glucose homeostasis is maintained by insulin-like signaling in a robust network of opposing and complementary signaling pathways. The hexosamine signaling pathway, terminating in O-linked-N-acetylglucosamine (O-GlcNAc) cycling, is a key...

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Autores principales: Mondoux, Michelle A., Love, Dona C., Ghosh, Salil K., Fukushige, Tetsunari, Bond, Michelle, Weerasinghe, Gayani R., Hanover, John A., Krause, Michael W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2011
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Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122314/
https://ncbi.nlm.nih.gov/pubmed/21441213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.126490
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