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Functional analysis of defined mutations in the immunoglobulin heavy-chain enhancer in transgenic mice.

We have analyzed the effect of defined mutations in the mouse immunoglobulin heavy-chain enhancer after introduction into the germline of transgenic mice. We have tested a mutation of the enhancer octamer motif, a double mutation of the octamer motif and the microB-site, and a triple mutation in the...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Annweiler, A, Müller, U, Wirth, T
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1992
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312230/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1579442/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.7.1503
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