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Functional analysis of defined mutations in the immunoglobulin heavy-chain enhancer in transgenic mice.

We have analyzed the effect of defined mutations in the mouse immunoglobulin heavy-chain enhancer after introduction into the germline of transgenic mice. We have tested a mutation of the enhancer octamer motif, a double mutation of the octamer motif and the microB-site, and a triple mutation in the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Annweiler, A, Müller, U, Wirth, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC312230/
https://ncbi.nlm.nih.gov/pubmed/1579442
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