Secretion of Endoplasmic Reticulum Aminopeptidase 1 Is Involved in the Activation of Macrophages Induced by Lipopolysaccharide and Interferon-γ

Endoplasmic reticulum aminopeptidase 1 (ERAP1) is a multifunctional enzyme with an important role in processing antigenic peptides presented to class I major histocompatibility complex in the endoplasmic reticulum. In this study, we found that endoplasmic reticulum-retained ERAP1 was secreted from m...

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Detalhes bibliográficos
Main Authors: Goto, Yoshikuni, Ogawa, Kenji, Hattori, Akira, Tsujimoto, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122245/
https://ncbi.nlm.nih.gov/pubmed/21531727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.239111
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