Streptococcus pyogenes M49 Plasminogen/Plasmin Binding Facilitates Keratinocyte Invasion via Integrin-Integrin-linked Kinase (ILK) Pathways and Protects from Macrophage Killing

The entry into epithelial cells and the prevention of primary immune responses are a prerequisite for a successful colonization and subsequent infection of the human host by Streptococcus pyogenes (group A streptococci, GAS). Here, we demonstrate that interaction of GAS with plasminogen promotes an...

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Autores principales: Siemens, Nikolai, Patenge, Nadja, Otto, Juliane, Fiedler, Tomas, Kreikemeyer, Bernd
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122219/
https://ncbi.nlm.nih.gov/pubmed/21521694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.202671
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