ERp29 Regulates ΔF508 and Wild-type Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Trafficking to the Plasma Membrane in Cystic Fibrosis (CF) and Non-CF Epithelial Cells

Sodium 4-phenylbutyrate (4PBA) improves the intracellular trafficking of ΔF508-CFTR in cystic fibrosis (CF) epithelial cells. The underlying mechanism is uncertain, but 4PBA modulates the expression of some cytosolic molecular chaperones. To identify other 4PBA-regulated proteins that might regulate...

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Detalhes bibliográficos
Main Authors: Suaud, Laurence, Miller, Katelyn, Alvey, Lora, Yan, Wusheng, Robay, Amal, Kebler, Catherine, Kreindler, James L., Guttentag, Susan, Hubbard, Michael J., Rubenstein, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122184/
https://ncbi.nlm.nih.gov/pubmed/21525008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.240267
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