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Increased Acetylation in the DNA-binding Domain of TR4 Nuclear Receptor by the Coregulator ARA55 Leads to Suppression of TR4 Transactivation

The nuclear receptor TR4 is a key regulator for many physiological processes, including growth, development, and metabolism. However, how the transcriptional activity of TR4 is regulated in the absence of ligand(s) remains largely unknown. Here we found that an androgen receptor (AR) coactivator, AR...

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Detalhes bibliográficos
Main Authors: Xie, Shaozhen, Ni, Jing, Lee, Yi-Fen, Liu, Su, Li, Gonghui, Shyr, Chih-Rong, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122174/
https://ncbi.nlm.nih.gov/pubmed/21515881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208181
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