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Reciprocal influence of the p53 and the hypoxic pathways
When cells sense a decrease in oxygen availability (hypoxia), they develop adaptive responses in order to sustain this condition and survive. If hypoxia lasts too long or is too severe, the cells eventually die. Hypoxia is also known to modulate the p53 pathway, in a manner dependent or not of HIF-1...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122125/ https://ncbi.nlm.nih.gov/pubmed/21614094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.48 |
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