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Prdm14 initiates lymphoblastic leukemia after expanding a population of cells resembling common lymphoid progenitors

Understanding the heterogeneous genetic mechanisms of tumor initiation in lymphoid leukemias (LL) will lead to improvements in prognostic classification and treatment regimens. In previous studies of mouse leukemias, we showed that retroviral insertion at the Evi32 locus leads to increased expressio...

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Autors principals: Dettman, E.J., Simko, Stephen J., Ayanga, Bernard, Carofino, Brandi, Margolin, Judith, Morse, Herbert C., Justice, Monica J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121925/
https://ncbi.nlm.nih.gov/pubmed/21339739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.12
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