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Use of fully modified 2′-O-methyl antisense oligos for loss-of-function studies in vertebrate embryos
Antisense oligonucleotides are commonly employed to study the roles of genes in development. Although morpholino phosphorodiamidate oligonucleotides (morpholinos) are widely used to block translation or splicing of target gene products, the usefulness of other modifications in mediating RNase-H inde...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121920/ https://ncbi.nlm.nih.gov/pubmed/21442720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20689 |
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