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Regulation of Protease-activated Receptor Signaling by Posttranslational Modifications

Protease-activated receptors (PARs) are a unique family of G protein-coupled receptors (GPCRs) that are irreversibly activated following proteolytic cleavage of their extracellular N-terminus. PARs play critical functions in hemostasis, thrombosis, inflammation, embryonic development and cancer prog...

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Hlavní autoři: Grimsey, Neil, Soto, Antonio G., Trejo, JoAnn
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121918/
https://ncbi.nlm.nih.gov/pubmed/21438117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.442
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