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Regulation of Protease-activated Receptor Signaling by Posttranslational Modifications
Protease-activated receptors (PARs) are a unique family of G protein-coupled receptors (GPCRs) that are irreversibly activated following proteolytic cleavage of their extracellular N-terminus. PARs play critical functions in hemostasis, thrombosis, inflammation, embryonic development and cancer prog...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121918/ https://ncbi.nlm.nih.gov/pubmed/21438117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.442 |
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