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Antagonism of Nerve Growth Factor-TrkA Signaling and the Relief of Pain

Nerve growth factor (NGF) was originally discovered as a neurotrophic factor essential for the survival of sensory and sympathetic neurons during development. However in the adult, NGF has been found to play an important role in nociceptor sensitization following tissue injury. Here we outline mecha...

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Detalhes bibliográficos
Main Authors: Mantyh, Patrick W., Koltzenburg, Martin, Mendell, Lorne M., Tive, Leslie, Shelton, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121917/
https://ncbi.nlm.nih.gov/pubmed/21602663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31821b1ac5
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