Pathogenesis of Renal Injury in the Megabladder Mouse: A Genetic Model of Congenital Obstructive Nephropathy

Congenital obstructive nephropathy (CON) is the most common cause of chronic renal failure in children, often leading to end stage renal disease. The megabladder (mgb) mouse exhibits signs of urinary tract obstruction in utero resulting in the development of hydroureteronephrosis and progressive ren...

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Main Authors: Ingraham, Susan E., Saha, Monalee, Carpenter, Ashley R., Robinson, Melissa, Ismail, Ihab, Singh, Sunita, Hains, David, Robinson, Michael L., Hirselj, Daniel A., Koff, Stephen A., Bates, Carlton M., McHugh, Kirk M.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121911/
https://ncbi.nlm.nih.gov/pubmed/20736884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3181f82f15
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