High incidence of vesico-ureteral reflux in mice with deletion of fibroblast growth factor receptor 2 in kidney mesenchyme

PURPOSE: Mice with conditional deletion of fibroblast growth factor receptor 2 (Fgfr2) in metanephric mesenchyme (Fgfr2(Mes−/−)) have ureteric bud induction abnormalities. Our goal was to determine if Fgfr2(Mes−/−) mutants developed abnormally positioned ureters predisposing to vesico-ureteral reflu...

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Hauptverfasser: Hains, David S., Sims-Lucas, Sunder, Carpenter, Ashley, Saha, Monalee, Murawski, Inga, Kish, Kayle, Gupta, Indra, McHugh, Kirk, Bates, Carlton M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657704/
https://ncbi.nlm.nih.gov/pubmed/20303521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2009.12.095
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