Glycosaminoglycan Binding Facilitates Entry of a Bacterial Pathogen into Central Nervous Systems

Certain microbes invade brain microvascular endothelial cells (BMECs) to breach the blood-brain barrier (BBB) and establish central nervous system (CNS) infection. Here we use the leading meningitis pathogen group B Streptococcus (GBS) together with insect and mammalian infection models to probe a p...

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Detalhes bibliográficos
Main Authors: Chang, Yung-Chi, Wang, Zhipeng, Flax, Lindsay A., Xu, Ding, Esko, Jeffrey D., Nizet, Victor, Baron, Miriam J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121876/
https://ncbi.nlm.nih.gov/pubmed/21731486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002082
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