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Host and Pathogen Glycosaminoglycan-Binding Proteins Modulate Antimicrobial Peptide Responses in Drosophila melanogaster

During group B streptococcal infection, the alpha C protein (ACP) on the bacterial surface binds to host cell surface heparan sulfate proteoglycans (HSPGs) and facilitates entry of bacteria into human epithelial cells. Previous studies in a Drosophila melanogaster model showed that binding of ACP to...

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Autors principals: Wang, Zhipeng, Flax, Lindsay A., Kemp, Melissa M., Linhardt, Robert J., Baron, Miriam J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028840/
https://ncbi.nlm.nih.gov/pubmed/21078848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00254-10
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