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Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6

In response to physiological stimuli, skeletal muscle alters its myofiber composition to significantly affect muscle performance and metabolism. This process requires concerted regulation of myofiber-specific isoforms of sarcomeric and calcium regulatory proteins that couple action potentials to the...

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Autors principals: Quiat, Daniel, Voelker, Kevin A., Pei, Jimin, Grishin, Nick V., Grange, Robert W., Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121857/
https://ncbi.nlm.nih.gov/pubmed/21633012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107413108
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