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Preexisting drug-resistance mutations reveal unique barriers to resistance for distinct antivirals
Clinical trials of direct-acting antiviral agents in patients chronically infected with hepatitis C virus (HCV) have demonstrated that viral resistance is detected rapidly during monotherapy. In patients, HCV does not exist as a single, genetically homogenous virus but rather as a population of vari...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121856/ https://ncbi.nlm.nih.gov/pubmed/21646519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101515108 |
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