RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions

Prokaryotes have evolved multiple versions of an RNA-guided adaptive immune system that targets foreign nucleic acids. In each case, transcripts derived from clustered regularly interspaced short palindromic repeats (CRISPRs) are thought to selectively target invading phage and plasmids in a sequenc...

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Detalhes bibliográficos
Main Authors: Wiedenheft, Blake, van Duijn, Esther, Bultema, Jelle B., Waghmare, Sakharam P., Zhou, Kaihong, Barendregt, Arjan, Westphal, Wiebke, Heck, Albert J. R., Boekema, Egbert J., Dickman, Mark J., Doudna, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121849/
https://ncbi.nlm.nih.gov/pubmed/21536913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102716108
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