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Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development

What makes embryogenesis a robust and canalized process is an important question in developmental biology. A bone morphogenetic protein (BMP) morphogen gradient plays a key role in embryonic development, and we are beginning to understand how the self-regulating properties of its signaling circuitry...

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Bibliografische gegevens
Hoofdauteurs: Paulsen, Malte, Legewie, Stefan, Eils, Roland, Karaulanov, Emil, Niehrs, Christof
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121836/
https://ncbi.nlm.nih.gov/pubmed/21633009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100179108
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