Sequence Imputation of HPV16 Genomes for Genetic Association Studies

BACKGROUND: Human Papillomavirus type 16 (HPV16) causes over half of all cervical cancer and some HPV16 variants are more oncogenic than others. The genetic basis for the extraordinary oncogenic properties of HPV16 compared to other HPVs is unknown. In addition, we neither know which nucleotides var...

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Main Authors: Smith, Benjamin, Chen, Zigui, Reimers, Laura, van Doorslaer, Koenraad, Schiffman, Mark, DeSalle, Rob, Herrero, Rolando, Yu, Kai, Wacholder, Sholom, Wang, Tao, Burk, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121793/
https://ncbi.nlm.nih.gov/pubmed/21731721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021375
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