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Lack of heterogeneity of HPV16 E7 sequence compared with HPV31 and HPV73 may be related to its unique carcinogenic properties

To assess the role of human papillomavirus virus (HPV) genetics in cervical lesions, we sequenced the E7 gene of HPV16, 31, or 73 from singly infected women who (1) cleared the infection quickly, (2) had type-specific persistent infection, or (3) progressed to CIN2 or worse lesions. Four of the 296...

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Detalhes bibliográficos
Main Authors: Safaeian, Mahboobeh, Doorslaer, Koenraad van, Schiffman, Mark, Chen, Zigui, Rodriguez, Ana Cecilia, Herrero, Rolando, Hildesheim, Allan, Burk, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852682/
https://ncbi.nlm.nih.gov/pubmed/20049619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-009-0579-2
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