Trafficking and Gating of Hyperpolarization-activated Cyclic Nucleotide-gated Channels Are Regulated by Interaction with Tetratricopeptide Repeat-containing Rab8b-interacting Protein (TRIP8b) and Cyclic AMP at Distinct Sites

Ion channel trafficking and gating are often influenced by interactions with auxiliary subunits. Tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) is an auxiliary subunit for neuronal hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. TRIP8b interacts directly w...

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Detalhes bibliográficos
Principais autores: Han, Ye, Noam, Yoav, Lewis, Alan S., Gallagher, Johnie J., Wadman, Wytse J., Baram, Tallie Z., Chetkovich, Dane M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121500/
https://ncbi.nlm.nih.gov/pubmed/21504900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236125
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