Dual Conserved Periplasmic Loops Possess Essential Charge Characteristics That Support a Catch-and-Release Mechanism of O-antigen Polymerization by Wzy in Pseudomonas aeruginosa PAO1

Heteropolymeric B-band lipopolysaccharide in Pseudomonas aeruginosa PAO1 is synthesized via the so-called Wzy-dependent pathway, requiring a functional Wzy for polymerization of O-antigen repeat units in the periplasm. Wzy is an integral inner membrane protein for which the detailed topology has bee...

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Autores principales: Islam, Salim T., Gold, Alexander C., Taylor, Véronique L., Anderson, Erin M., Ford, Robert C., Lam, Joseph S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Membrane Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121466/
https://ncbi.nlm.nih.gov/pubmed/21498511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.204651
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