Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides noxius Hoffmann by a Human-derived Single-chain Antibody Fragment

It has previously been reported that several single-chain antibody fragments of human origin (scFv) neutralize the effects of two different scorpion venoms through interactions with the primary toxins of Centruroides noxius Hoffmann (Cn2) and Centruroides suffusus suffusus (Css2). Here we present th...

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Main Authors: Canul-Tec, Juan Carlos, Riaño-Umbarila, Lidia, Rudiño-Piñera, Enrique, Becerril, Baltazar, Possani, Lourival D., Torres-Larios, Alfredo
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121463/
https://ncbi.nlm.nih.gov/pubmed/21489992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238410
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