Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides noxius Hoffmann by a Human-derived Single-chain Antibody Fragment

It has previously been reported that several single-chain antibody fragments of human origin (scFv) neutralize the effects of two different scorpion venoms through interactions with the primary toxins of Centruroides noxius Hoffmann (Cn2) and Centruroides suffusus suffusus (Css2). Here we present th...

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Detalles Bibliográficos
Main Authors: Canul-Tec, Juan Carlos, Riaño-Umbarila, Lidia, Rudiño-Piñera, Enrique, Becerril, Baltazar, Possani, Lourival D., Torres-Larios, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121463/
https://ncbi.nlm.nih.gov/pubmed/21489992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238410
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