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Structure-Function Analysis of the OB and Latch Domains of Chlorella Virus DNA Ligase

Chlorella virus DNA ligase (ChVLig) is a minimized eukaryal ATP-dependent DNA sealing enzyme with an intrinsic nick-sensing function. ChVLig consists of three structural domains, nucleotidyltransferase (NTase), OB-fold, and latch, that envelop the nicked DNA as a C-shaped protein clamp. The OB domai...

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Autori principali: Samai, Poulami, Shuman, Stewart
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121408/
https://ncbi.nlm.nih.gov/pubmed/21527793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245399
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