Molecular Characterization of the Interaction between Sialylated Neisseria gonorrhoeae and Factor H

Human factor H (HufH), a key inhibitor of the alternative pathway of complement, binds to Neisseria gonorrhoeae and constitutes an important mechanism of human-specific complement evasion. The C-terminal domain 20 of HufH contains the binding site for sialylated gonococci. We exploited differences i...

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Bibliografski detalji
Glavni autori: Shaughnessy, Jutamas, Ram, Sanjay, Bhattacharjee, Arnab, Pedrosa, Joana, Tran, Connie, Horvath, Gabor, Monks, Brian, Visintin, Alberto, Jokiranta, T. Sakari, Rice, Peter A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Microbiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121369/
https://ncbi.nlm.nih.gov/pubmed/21531728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225516
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