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Progesterone Impairs Human Ether-a-go-go-related Gene (HERG) Trafficking by Disruption of Intracellular Cholesterol Homeostasis

The prolongation of QT intervals in both mothers and fetuses during the later period of pregnancy implies that higher levels of progesterone may regulate the function of the human ether-a-go-go-related gene (HERG) potassium channel, a key ion channel responsible for controlling the length of QT inte...

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Detalhes bibliográficos
Main Authors: Wu, Zhi-Yuan, Yu, De-Jie, Soong, Tuck Wah, Dawe, Gavin S., Bian, Jin-Song
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121363/
https://ncbi.nlm.nih.gov/pubmed/21525004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198853
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