Pilot Pharmacokinetic and Dosimetric Studies of (18)F-FPPRGD2: A PET Radiopharmaceutical Agent for Imaging α(v)β(3) Integrin Levels

PURPOSE: To assess the safety, biodistribution, and dosimetric properties of the positron emission tomography (PET) radiopharmaceutical agent fluorine 18 ((18)F) FPPRGD2 (2-fluoropropionyl labeled PEGylated dimeric RGD peptide [PEG3-E{c(RGDyk)}2]), which is based on the dimeric arginine-glycine–aspa...

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Detalles Bibliográficos
Main Authors: Mittra, Erik S., Goris, Michael L., Iagaru, Andrei H., Kardan, Arash, Burton, Lindee, Berganos, Rhona, Chang, Edwin, Liu, Shuanglong, Shen, Bin, Chin, Frederick T., Chen, Xiaoyuan, Gambhir, Sanjiv S.
Formato: Artigo
Idioma:Inglês
Publicado: Radiological Society of North America, Inc. 2011
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121013/
https://ncbi.nlm.nih.gov/pubmed/21502381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.11101139
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