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Generation of Axin1 Conditional Mutant Mice
Axin1 is a critical negative regulator of the canonical Wnt-signaling pathway. It is a concentration-limiting factor in the β-catenin degradation complex. Axin1 null mutant mouse embryos died at embryonic day 9.5, precluding direct genetic analysis of the roles of Axin1 in many developmental and phy...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3120898/ https://ncbi.nlm.nih.gov/pubmed/21344612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20703 |
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