Multiple Insulin Degrading Enzyme Variants Alter In Vitro Reporter Gene Expression

The insulin degrading enzyme (IDE) variant, v311 (rs6583817), is associated with increased post-mortem cerebellar IDE mRNA, decreased plasma β-amyloid (Aβ), decreased risk for Alzheimer's disease (AD) and increased reporter gene expression, suggesting that it is a functional variant driving inc...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Belbin, Olivia, Crump, Michael, Bisceglio, Gina D., Carrasquillo, Minerva M., Morgan, Kevin, Younkin, Steven G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120874/
https://ncbi.nlm.nih.gov/pubmed/21731745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021429
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker