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AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice
BACKGROUND: Acute ozone exposure causes lung oxidative stress and inflammation leading to lung injury. At least one mechanism underlying the lung toxicity of ozone involves excessive production of reactive oxygen and nitrogen intermediates such as peroxynitrite. In addition and beyond its major proo...
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Главные авторы: | , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
BioMed Central
2011
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Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3120668/ https://ncbi.nlm.nih.gov/pubmed/21595935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-64 |
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