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AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice

BACKGROUND: Acute ozone exposure causes lung oxidative stress and inflammation leading to lung injury. At least one mechanism underlying the lung toxicity of ozone involves excessive production of reactive oxygen and nitrogen intermediates such as peroxynitrite. In addition and beyond its major proo...

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Библиографические подробности
Главные авторы: Hulo, Sébastien, Tiesset, Hélène, Lancel, Steve, Viollet, Benoit, Sobaszek, Annie, Nevière, Rémi
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120668/
https://ncbi.nlm.nih.gov/pubmed/21595935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-64
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