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AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice

BACKGROUND: Acute ozone exposure causes lung oxidative stress and inflammation leading to lung injury. At least one mechanism underlying the lung toxicity of ozone involves excessive production of reactive oxygen and nitrogen intermediates such as peroxynitrite. In addition and beyond its major proo...

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Detalhes bibliográficos
Main Authors: Hulo, Sébastien, Tiesset, Hélène, Lancel, Steve, Viollet, Benoit, Sobaszek, Annie, Nevière, Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120668/
https://ncbi.nlm.nih.gov/pubmed/21595935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-64
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