Therapeutic potential of N-acetylcysteine as an antiplatelet agent in patients with type-2 diabetes

BACKGROUND: Platelet hyperaggregability is a pro-thrombotic feature of type-2 diabetes, associated with low levels of the antioxidant glutathione (GSH). Clinical delivery of N-acetylcysteine (NAC), a biosynthetic precursor of GSH, may help redress a GSH shortfall in platelets, thereby reducing throm...

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Bibliografiske detaljer
Main Authors: Gibson, Kyle R, Winterburn, Tim J, Barrett, Fiona, Sharma, Sushma, MacRury, Sandra M, Megson, Ian L
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120650/
https://ncbi.nlm.nih.gov/pubmed/21600014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-10-43
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