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2-arachidonyl glycerol activates platelets via conversion to arachidonic acid and not by direct activation of cannabinoid receptors

AIMS: Cannabinoid receptor-1 (CB(1)) antagonists suppress appetite and induce weight loss. Direct antagonism of CB(1) receptors on platelets might be an additional benefit for CB(1) antagonists, but the role of CB(1) receptors in platelets is controversial. We tested the hypothesis that the endocann...

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Detalhes bibliográficos
Main Authors: Keown, Oliver P, Winterburn, Timothy J, Wainwright, Cherry L, Macrury, Sandra M, Neilson, Ilene, Barrett, Fiona, Leslie, Stephen J, Megson, Ian L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911548/
https://ncbi.nlm.nih.gov/pubmed/20653671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03697.x
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