Chronic morphine induces the concomitant phosphorylation and altered association of multiple signaling proteins: A novel mechanism for modulating cell signaling

Traditional mechanisms thought to underlie opioid tolerance include receptor phosphorylation/down-regulation, G-protein uncoupling, and adenylyl cyclase superactivation. A parallel line of investigation also indicates that opioid tolerance development results from a switch from predominantly opioid...

Full description

Saved in:
Bibliographic Details
Main Authors: Chakrabarti, Sumita, Oppermann, Martin, Gintzler, Alan R.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC31204/
https://ncbi.nlm.nih.gov/pubmed/11274443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071031798
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items