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Selective cleavage of closely-related mRNAs by synthetic ribozymes.
In Phaseolus vulgaris L. (French bean) glutamine synthetase (GS) is encoded by four closely-related genes termed gln-alpha, gln-beta, gln-gamma and gln-delta. We have constructed and characterised in vitro a number of hammerhead ribozymes designed to cleave individual RNAs encoded by these genes. Th...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1992
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312025/ https://ncbi.nlm.nih.gov/pubmed/1347418 |
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