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Selective cleavage of closely-related mRNAs by synthetic ribozymes.

In Phaseolus vulgaris L. (French bean) glutamine synthetase (GS) is encoded by four closely-related genes termed gln-alpha, gln-beta, gln-gamma and gln-delta. We have constructed and characterised in vitro a number of hammerhead ribozymes designed to cleave individual RNAs encoded by these genes. Th...

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Publicat a:Nucleic Acids Res
Autors principals: Bennett, M J, Cullimore, J V
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1992
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1347418/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.4.831
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