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Adenosine hypothesis of schizophrenia –opportunities for pharmacotherapy

Pharmacotherapy of schizophrenia based on the dopamine hypothesis remains unsatisfactory for the negative and cognitive symptoms of the disease. Enhancing N-methyl-d-aspartate receptors (NMDAR) function is expected to alleviate such persistent symptoms, but successful development of novel clinically...

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Bibliographic Details
Main Authors: Boison, Detlev, Singer, Philipp, Shen, Hai-Ying, Feldon, Joram, Yee, Benjamin K.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119785/
https://ncbi.nlm.nih.gov/pubmed/21315743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.01.048
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