A role for IL-27 in limiting T regulatory cell populations

IL-27 is a cytokine that regulates Th function during autoimmune and pathogen-induced immune responses. Although previous studies have shown that T regulatory cells (T(reg)) express the IL-27R, and that IL-27 inhibits forkhead box P3 upregulation in vitro, little is known about how IL-27 influences...

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Detalhes bibliográficos
Main Authors: Tait Wojno, Elia D., Hosken, Nancy, Stumhofer, Jason S., O’Hara, Aisling C., Mauldin, Elizabeth, Fang, Qun, Turka, Laurence A., Levin, Steven D., Hunter, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119737/
https://ncbi.nlm.nih.gov/pubmed/21622862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004182
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