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Cellular competition independent of BAFF/BLyS results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartments
The peripheral B cell pro-survival cytokine BAFF/BLyS has been proposed to participate in the regulation of immunological tolerance. Selective elimination or reconstitution of B cells expressing transgene-encoded, autoreactive BCRs upon systemic BLyS depletion or supplementation, respectively, was o...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119736/ https://ncbi.nlm.nih.gov/pubmed/21632709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003924 |
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