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In vivo BLyS/BAFF Neutralization Ameliorates Islet-Directed Autoimmunity in Non-Obese Diabetic (NOD) Mice
B-lymphocytes are required for the pathogenesis of autoimmune diabetes in NOD mice. Previous studies established that a lymphopenic transitional (TR) B-cell compartment reduces the competitive constraint on the entry of newly emerging TR B-cells into the splenic follicle (FO), thereby disrupting a p...
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| Glavni autori: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586964/ https://ncbi.nlm.nih.gov/pubmed/19018006 |
| Oznake: |
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