Critical Transition in Tissue Homeostasis Accompanies Murine Lung Senescence

BACKGROUND: Respiratory dysfunction is a major contributor to morbidity and mortality in aged populations. The susceptibility to pulmonary insults is attributed to “low pulmonary reserve”, ostensibly reflecting a combination of age-related musculoskeletal, immunologic and intrinsic pulmonary dysfunc...

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Main Authors: Calvi, Carla L., Podowski, Megan, D'Alessio, Franco R., Metzger, Shana L., Misono, Kaori, Poonyagariyagorn, Hataya, Lopez-Mercado, Armando, Ku, Therese, Lauer, Thomas, Cheadle, Christopher, Talbot, C. Conover, Jie, Chunfa, McGrath-Morrow, Sharon, King, Landon S., Walston, Jeremy, Neptune, Enid R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119663/
https://ncbi.nlm.nih.gov/pubmed/21713037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020712
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