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Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia

Increased oxidative stress is associated with perinatal asphyxia and respiratory distress in the newborn period. Induction of nuclear factor erythroid 2 p45-related factor (Nrf2) has been shown to decrease oxidative stress through the regulation of specific gene pathways. We hypothesized that Nrf2 a...

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Détails bibliographiques
Auteurs principaux: McGrath-Morrow, Sharon, Lauer, Thomas, Yee, Min, Neptune, Enid, Podowski, Megan, Thimmulappa, Rajesh K., O'Reilly, Michael, Biswal, Shyam
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670765/
https://ncbi.nlm.nih.gov/pubmed/19151108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90487.2008
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