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Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
G-quadruplexes are four-stranded DNA structures that are over-represented in gene promoter regions and are viewed as emerging therapeutic targets in oncology, as transcriptional repression of oncogenes through stabilization of these structures could be a novel anticancer strategy. Many gene promoter...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119469/ https://ncbi.nlm.nih.gov/pubmed/21455236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3428 |
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