Insulin receptor-related receptor as an extracellular alkali sensor

The insulin receptor-related receptor (IRR), an orphan receptor tyrosine kinase of the insulin receptor family, can be activated by alkaline media both in vitro and in vivo at pH>7.9. The alkali-sensing property of IRR is conserved in frog, mouse and human. IRR activation is specific, dose-depend...

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Main Authors: Deyev, Igor E., Sohet, Fabien, Vassilenko, Konstantin P., Serova, Oxana V., Popova, Nadezhda V., Zozulya, Sergey A., Burova, Elena B., Houillier, Pascal, Rzhevsky, Dmitry I., Berchatova, Anastasiya A., Murashev, Arkady N., Chugunov, Anton O., Efremov, Roman G., Nikol’sky, Nikolai N., Bertelli, Eugenio, Eladari, Dominique, Petrenko, Alexander G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119365/
https://ncbi.nlm.nih.gov/pubmed/21641549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.03.022
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