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Apical deficiency triggers JNK-dependent apoptosis in the embryonic epidermis of Drosophila

Epithelial homeostasis and the avoidance of diseases such as cancer require the elimination of defective cells by apoptosis. Here, we investigate how loss of apical determinants triggers apoptosis in the embryonic epidermis of Drosophila. Transcriptional profiling and in situ hybridisation show that...

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Bibliografische gegevens
Hoofdauteurs: Kolahgar, Golnar, Bardet, Pierre-Luc, Langton, Paul F., Alexandre, Cyrille, Vincent, Jean-Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Company of Biologists 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119309/
https://ncbi.nlm.nih.gov/pubmed/21693518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.059980
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