Drosophila happyhour modulates JNK-dependent apoptosis

Mitogen-activated protein kinase kinase kinase kinase-3 (MAP4K3) is a Ste20 kinase family member that modulates multiple signal transduction pathways. We recently identified MAP4K3 as proapoptotic kinase using an RNA interference screening approach. In mammalian cells, MAP4K3 enhances the mitochondr...

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Detaylı Bibliyografya
Asıl Yazarlar: Lam, D, Shah, S, de Castro, I P, Loh, S H Y, Martins, L M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2010
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032524/
https://ncbi.nlm.nih.gov/pubmed/21364671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.44
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